Hydroxychloroquine (plaquenil) is an old antimalarial agent that has immunomodulatory effects widely used in SLE, in which it decreases mortality and the likelihood of developing lupus nephritis, a very common complication of SLE. It works by inhibiting the processing effects of peptide antigens and their assembly into major histocompatibility complex by antigen presenting cells.
Hydroxychloroquine (plaquenil) is an old antimalarial agent that has immunomodulatory effects widely used in SLE, in which it decreases mortality and the likelihood of developing lupus nephritis, a very common complication of SLE. It works by inhibiting the processing effects of peptide antigens and their assembly into major histocompatibility complex by antigen presenting cells.
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